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G418硫酸盐
G418 sulfate
KS1019
108321-42-2
BR，600ug/mg
Art.No. Specifications Price Member Price Stock Quantity Cart
KS1019-100mg BR，600ug/mg ¥56.05
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KS1019-250mg BR，600ug/mg ¥92.15
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KS1019-1g BR，600ug/mg ¥227.05
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KS1019-5g BR，600ug/mg ¥1117.20
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KS1019-25g BR，600ug/mg ¥5324.75
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Chinese Name G418硫酸盐
English Name G418 sulfate
CAS No. 108321-42-2
Storage 2-8℃
Use To 抑制蛋白质合成来杀灭细菌、抑制细胞的生长和分裂
Pay Attention To 仅用于科学研究
GHS
Hazardous Chemical
Class
Warning Statement
UNub
Hazard Statement
Hazard Category Code

G418硫酸盐是一种广谱抗生素，常用于细胞培养和分子生物学领域。它主要通过抑制蛋白质合成来杀灭细菌或抑制细胞的生长和分裂。G418硫酸盐的具体作用：

1. 选择性抗生素：G418硫酸盐作为一种广谱抗生素，对细菌和真菌的抑制作用较强。

2. 筛选抗性细胞：G418硫酸盐可以干扰细胞内的核苷酸代谢，从而导致细胞DNA合成和蛋白质合成的抑制，使得非常规细胞不能生长或繁殖，而抗性细胞则可以生长和繁殖。因此，G418硫酸盐可以被用于筛选具有抗药性的细胞株，比如在基因转染、基因敲除等实验过程中，可用G418硫酸盐筛选。

3. 蛋白质表达：在蛋白质表达实验中，G418硫酸盐通常被加入细胞培养基中，以筛选表达目的蛋白质的细胞株。

G418硫酸盐作为一种广谱抗生素和选择性毒死剂，在细胞培养和分子生物学实验中广泛应用，具有筛选抗性细胞和表达目的蛋白质等多个应用方面。

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