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两性霉素B
Amphotericin B
KS1013
1397-89-3
USP级，750mg/g
Art.No. Specifications Price Member Price Stock Quantity Cart
KS1013-1g USP级，750mg/g ¥91.20
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KS1013-5g USP级，750mg/g ¥366.70
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KS1013-25g USP级，750mg/g ¥1103.90
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KS1013-100g USP级，750mg/g ¥3642.30
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Chinese Name 两性霉素B
English Name Amphotericin B
CAS No. 1397-89-3
Storage 2-8℃，避光
Use To 与真菌细胞膜的主要成分--ergosterol相关，破坏真菌的细胞膜结构，从而破坏真菌细胞，并导致真菌细胞的凋亡
Pay Attention To 仅用于科学研究
GHS
Hazardous Chemical
Class
Warning Statement
UNub
Hazard Statement
Hazard Category Code

两性霉素B（Amphotericin B）是一种广谱抗真菌药物，通常用于治疗严重的真菌感染。它的主要作用是通过与真菌细胞膜的主要成分--ergosterol相关，破坏真菌的细胞膜结构，从而破坏真菌细胞，并导致真菌细胞的凋亡。

两性霉素B的主要用途包括：

1. 治疗真菌性血症：如念珠菌属、曲霉菌属等引起的血液感染。

2. 治疗真菌性脑膜炎：如念珠菌性脑膜炎等。

3. 治疗深部真菌感染：如念珠菌性感染、曲霉感染、组织胞浆菌病等。

4. 治疗其他真菌感染：如肺真菌感染、皮肤真菌感染等。

尽管两性霉素B是一种有效的药物，但由于其广谱性和毒性较高，使用时需特别小心。它通常供静脉注射而不被口服，因为它会导致一些严重的不良反应，比如肾脏损害、电解质失衡等。

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